Expanding the pathway

The Rb/E2F pathway: expanding roles and emerging paradigms.

Expanding the repertoire of biofuel alternatives through metabolic pathway evolution.

A multitude of concerns that include climate change, political instability, and depletion of petroleum resources has recently ignited renewed interest in fossil fuel alternatives (1). As a result, microbial systems have been extensively explored and successfully used for the biosynthesis of some biofuels, most notably ethanol (2, 3). Higher-chain alcohols, however, offer several advantages comp...

Developing a Textbook Evaluation Scheme for the Expanding Circle

Among the four important factors in the educational contexts, namely, teachers, learners, textbooks and contexts, textbooks play an important role in English Language Teaching (ELT), particularly in the English as a Foreign Language (EFL) classroom where it provides the primary source of linguistic input. The wealth of published material for English language teaching (ELT) available in the mark...

Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis.

Oxidation products of low-density lipoproteins have been suggested to promote inflammation during atherogenesis, and reticulocyte-type 15-lipoxygenase has been implicated to mediate this oxidation. In addition, the 5-lipoxygenase cascade leads to formation of leukotrienes, which exhibit strong proinflammatory activities in cardiovascular tissues. Here, we studied both lipoxygenase pathways in h...

Expanding Saga of the Renin-Angiotensin System: The Angiotensin II Counter-Regulatory AT2 Receptor Pathway.

T he search for hidden truths behind established concepts and dogma is often a never-ending, uphill climb, and the history of science and medicine is full of examples of this. " To raise new questions, new possibilities, to regard old questions from a new angle, requires creative imagination and marks real advances in science " (Albert Einstein). The story of the renin-angiotensin system (RAS),...